The 2022 Jeep Grand Cherokee 4XE is available in multiple trims, each with its own estimated fuel economy, here are the EPA estimates for each trim:

1. Base : 57 MPG City and 56 MPG Highway + battery range of 25 miles
2. Trailhawk : 57 MPG City and 56 MPG Highway + battery range of 26 miles
3. Overland : 57 MPG City and 56 MPG Highway + battery range of 25 miles
4. Summit : 57 MPG City and 56 MPG Highway + battery range of 26 miles
5. Summit Reserve : 57 MPG City and 56 MPG Highway + battery range of 25 miles

It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency.

The 2022 Jeep Grand Cherokee 4XE has a maximum towing capacity of between 3500 and 6000 pounds, when properly equipped. Various factors may impact towing capacity, including weight of passengers, cargo, and options/accessories.