The 2012 Mercedes-Benz E350 is available in multiple trims, each with its own estimated fuel economy, here are the EPA estimates for each trim:

1. : 19 MPG City and 29 MPG Highway
2. Luxury: 20 MPG City and 30 MPG Highway
3. Luxury: 21 MPG City and 32 MPG Highway
4. Sport: 20 MPG City and 30 MPG Highway
5. Sport: 21 MPG City and 32 MPG Highway

It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency.

The Mercedes-Benz E350 received a rating of 3.5 out of 5 stars from RepairPal, which RepairPal describes as Above Average. This rating ranks the Mercedes-Benz E350 as 9​​ out of 48​​ among Luxury Fullsize Car

The 2012 Mercedes-Benz E350 has received an average 4.6 out of 5 stars from our customers. If you're in the market for a 2012 Mercedes-Benz E350, check out reviews from customers just like you. 2012 Mercedes-Benz E350 Reviews.

The 2012 Mercedes-Benz E350 has a maximum towing capacity of 1654 pounds, when properly equipped. Various factors may impact towing capacity, including weight of passengers, cargo, and options/accessories.

Here is what's new for the 2012 Mercedes-Benz E350:

• Panoramic Sunroof
• Fold-Away Third Row
• Rear View Camera
• Third Row Seat
• Heated Steering Wheel

Here are the pros and cons of the 2012 Mercedes-Benz E350:

Pros	Cons
Ride and Handling Fuel Economy Styling	Cost to Maintain Value Seat Comfort