Which Mercedes-Benz CLE 450 gets the best gas mileage (mpg)?

The most fuel-efficient Mercedes-Benz CLE 450 is the 2025 Mercedes-Benz CLE 450 which gets 23 MPG City and 32 MPG Highway.

It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency. Fuel economy figures are based on EPA estimates for when vehicle sold as new. Fuel economy may vary for reasons like driving conditions and vehicle history. Unless specified, figures are for vehicles equipped with an automatic transmission. See fueleconomy.gov.

This price does not include tax, title, and tags. Additional fees may also apply depending on the state of purchase.