The 2018 Lexus GS 350 is available in multiple trims, each with its own estimated fuel economy, here are the EPA estimates for each trim:

1. Base: 20 MPG City and 28 MPG Highway
2. F-Sport: 19 MPG City and 27 MPG Highway

It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency.

The Lexus GS 350 received a rating of 4 out of 5 stars from RepairPal, which RepairPal describes as Excellent. This rating ranks the Lexus GS 350 as 1​​ out of 48​​ among Luxury Fullsize Car