<b>Q</b>: Which Lexus IS 500 gets the best gas mileage (mpg)?
A: The most fuel-efficient Lexus IS 500 is the 2022 Lexus IS 500 F-Sport Performance which gets 17 MPG City and 25 MPG Highway.
It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency. Fuel economy figures are based on EPA estimates for when vehicle sold as new. Fuel economy may vary for reasons like driving conditions and vehicle history. Unless specified, figures are for vehicles equipped with an automatic transmission. See fueleconomy.gov.
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