Which Lexus LS 500h gets the best gas mileage (mpg)?

The most fuel-efficient Lexus LS 500h is the 2021 Lexus LS 500h Base Hybrid which gets 25 MPG City and 33 MPG Highway.

It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency. Fuel economy figures are based on EPA estimates for when vehicle sold as new. Fuel economy may vary for reasons like driving conditions and vehicle history. Unless specified, figures are for vehicles equipped with an automatic transmission. See fueleconomy.gov.

This price does not include tax, title, and tags. Additional fees may also apply depending on the state of purchase.