The 2016 Mercedes-Benz E250 is available in multiple trims, each with its own estimated fuel economy, here are the EPA estimates for each trim:

1. Luxury: 28 MPG City and 42 MPG Highway
2. Sport: 28 MPG City and 42 MPG Highway

It is important to remember factors such as driving style, weather conditions, and the use of features such as Eco mode can impact fuel efficiency.

The 2016 Mercedes-Benz E250 has received an average 5.0 out of 5 stars from our customers. If you're in the market for a 2016 Mercedes-Benz E250, check out reviews from customers just like you. 2016 Mercedes-Benz E250 Reviews.

Here is what's new for the 2016 Mercedes-Benz E250:

• Satellite Radio Ready
• SiriusXM Trial Available

Here are the pros and cons of the 2016 Mercedes-Benz E250:

Pros	Cons
Fuel Economy Ride and Handling Reliability	Cost to Maintain