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2021 Mercedes-Benz GLS450 review

Research, photos, specs, and expertise

Mercedes-Benz GLS450 highlights

Customer rating

Mileage (EPA estimate)

20 city, 24 highway, 21 combined

Pricing for current inventory

(no current inventory)

Price
Year

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All Mercedes-Benz GLS450 years

What is new for the 2021 Mercedes-Benz GLS450?

  • GLS450 trims have been upgraded with Seat Massagers, A/C Seat(s), and 20 Inch Plus Wheels as standard equipment this year.
  • Run Flat Tires features are now available as options on select trims.

2021 Mercedes-Benz GLS450 trims

Curious how Mercedes-Benz GLS450 trims differ? Use our side-by-side vehicle comparison to see the differences and similarities

Base:

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Ratings & reliability

Customer ratings

3
1
2
Above Average

RepairPal gave the Mercedes-Benz GLS450 an overall reliability rating of 3.5 out of 5 stars, which RepairPal describes as Above Average. This rating ranks Mercedes-Benz GLS450 5th out of 20 among Luxury Fullsize SUVs.

View RepairPal's full rating of the Mercedes-Benz GLS450

2021 Mercedes-Benz GLS450 FAQ

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* Price excludes taxes, title, registration, and fees. Applicable transfer fees are due in advance of vehicle delivery and are separate from sales transactions.

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Statements of fuel economy or EV range are based on EPA and other third-party estimates for vehicles when new. Fuel economy and EV range will degrade with time and vary based on age, driving conditions, vehicle history, and other conditions. See fueleconomy.gov for more info.

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