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2022 Lexus RX 350 review

Research, photos, specs, and expertise

Lexus RX 350 highlights

Customer rating

Pros

  • Six USB ports for tech lovers
  • Tow ability for a small trailer
  • Leather and soft-touch plastics in the cabin

Cons

  • Awkward trackpad controller on infotainment system
  • Some Android apps won't sync
  • F Sport trim is bouncy on older roads

Mileage (EPA estimate)

18 city, 25 highway, 21 combined

Pricing for current inventory

(no current inventory)

Price
Year

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The 2022 Lexus RX prioritizes comfort and luxury

The 2022 Lexus RX 350 marks the end of the line for this fourth-generation model that was introduced in 2016. Over those years, it solidified its position as a comfortable and efficient alternative to the German brands, but time caught up with the RX. Besides this RX 350, there’s also a more efficient RX 450h hybrid as well as a three-row RX 350L that are reviewed separately.

There were no significant changes for the 2022 RX 350 since engineers were likely hard at work on the next-generation model. While this RX deserved praise for its high levels of overall comfort, it was held back by a very frustrating infotainment interface that technophiles could consider a deal breaker.

If you’re able to easily use that trackpad controller, perhaps the RX is the midsize luxury SUV you’ve been looking for. Otherwise, we’d steer you toward alternatives such as the BMW X3, Volvo XC60, or Mercedes-Benz GLE.

All Lexus RX 350 years

Not sure what year to select? Learn about each Lexus RX 350 generation from 2012 to 2026

What is new for the 2022 Lexus RX 350?

  • Trim Discontinued: [Specify the trim name] is no longer available.
  • Standard Equipment on all models now includes [list significant new standard features].
  • New Equipment added: [list new optional features that enhance value].
  • Improved fuel efficiency ratings for all models.
  • Enhanced safety features now standard across the lineup.

2022 Lexus RX 350 trims

Curious how Lexus RX 350 trims differ? Use our side-by-side vehicle comparison to see the differences and similarities

Base:

  • 295-hp, 267-lb-ft of torque 3.5L
  • Rear Defroster
  • Automated Cruise Control
  • Power Seats
  • Overhead Airbags
  • Power Mirrors
  • Traction Control
  • Leatherette Seats
  • Side Airbags
  • View our Lexus RX 350 inventory

L:

  • Includes all features available on the Base
  • 290-hp, 263-lb-ft of torque 3.5L
  • Rear Air Conditioning
  • Third Row Seat
  • Power Folding Third Row
  • View our Lexus RX 350 L inventory

F-Sport:

F-SPORT Handling:

L Luxury:

What We Like

Attractive and luxurious interior: The RX 350’s interior deserves praise for its handsome styling and high-quality materials, and it remained attractive and inviting throughout this generation’s life. You’d have a tough time finding a surface that wasn’t covered in either leather or a soft-touch plastic. It’s a solid entry among entry-level luxury SUVs and competitive against more expensive models.

Comfortable ride quality: For the most part, the Lexus RX 350 is focused more on comfort than performance and that has served this SUV well for decades. The suspension ably soaks up road imperfections and greatly reduces fatigue over long distances. The F Sport, on the other hand, attempts to add some handling performance with mixed results and that negatively affects comfort. It’s too stiff and gets jittery over rough surfaces.

Wide cargo space: With 18.4 cubic feet of available cargo capacity, the RX 350 isn’t as accommodating as some rivals, but it counters that with a more usable space. The cargo area's wide opening and floor make it much easier to load bulkier and heavier objects. For more room, the rear seats fold flat with the cargo floor. The RX is also rated to tow up to 3,500 pounds, when properly equipped.

What Needs Improvement

Frustrating infotainment interface: Lexus’ trackpad infotainment controller is legendary for all the wrong reasons. It’s one of our least favorite in any vehicle ever because it’s distracting and difficult to use when you're driving. It uses a similar pad that you’d find on a laptop and moves an on-screen cursor. Unlike a laptop, though, the RX is a moving object and trying to select your desired button is incredibly frustrating. This alone can be a deal breaker for some.

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Ratings & reliability

Customer ratings

The 2022 Lexus RX 350 receives high praise for its smooth ride, comfortable seating, solid performance, and reliable build quality. Technology features are appreciated but some find them overly complex. While highly rated for cabin quietness, critiques include average fuel efficiency and navigation controls. A solid choice for comfort and elegance.
4
1
2
Excellent

RepairPal gave the Lexus RX 350 an overall reliability rating of 4.5 out of 5 stars, which RepairPal describes as Excellent. This rating ranks Lexus RX 350 3rd out of 29 among Luxury Midsize SUVs.

View RepairPal's full rating of the Lexus RX 350

Lexus RX 350 features and specs

L Luxury 4D Sport Utility 2WD

Standard Features

  • Rear Air Conditioning
  • Rear Defroster
  • Automated Cruise Control
  • Third Row Seat
  • Power Folding Third Row
  • Power Locks
  • Power Windows
  • Sunroof(s)
  • Air Conditioning
  • ABS Brakes
  • Leather Seats
  • Power Seat(s)
  • Memory Seat(s)
  • Front Seat Heaters
  • Rear Seat Heaters
  • Power Mirrors
  • Traction Control
  • A/C Seat(s)
  • Side Airbags
  • Overhead Airbags
  • Heated Steering Wheel
  • Rear Sunshade
  • Rear View Camera
  • Blind Spot Monitor
  • Lane Departure Warning
  • Smart Key
  • Remote Start
  • Heated Mirrors
  • 20 Inch Plus Wheels
  • Power Hatch/Deck Lid
  • Alloy Wheels
  • Automatic Transmission
  • Bluetooth Technology
  • AM/FM Stereo
  • Satellite Radio Ready
  • Auxiliary Audio Input
  • CD Audio
  • Quad Seats
  • Head Up Display
  • Rear View Camera
  • Parking Sensors
  • Leather Seats
  • Full Roof Rack
  • Tow Hitch
  • Running Boards
  • Mark Levinson Sound
  • Apple CarPlay
  • Navigation System
  • Android Auto

Drive Wheels

Front Wheel Drive (2WD)

Engine size

3.5L

Horsepower

290

Torque (ft-lbs)

263

Engine type

Gas

Fuel capacity

19.2

Wheelbase

109.8"

Overall length

196.9"

Width

74.6"

Height

67.3"

Leg room

F 41.4"/M 30.9"/R 23.5"

Head room

F 38.7"/M 37.9"/R 34.8"

Front tires

P235/55VR20

Rear tires

P235/55VR20

Seating capacity

7

Transmission

Automatic

2022 Lexus RX 350 FAQ

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